Quantitation Of Specific Proteins In Blister Fluid

作者: Peter Schmid

DOI: 10.1111/1523-1747.EP12259948

关键词: ChemistryChromatographySerum albuminFibrinogenFriction blisterRadial immunodiffusionAlbuminDermisBiochemistryImmunodiffusionCantharidinCell biologyMolecular biologyDermatology

摘要: Radial immunodiffusion is used to determine specific proteins in friction blister fluid and cantharidin of human volunteers. Four (albumin, fibrinogen, immunoglobin IgG IgM) were determined pooled 2, 4 21 hours after blistering. The same also from the back palm. concentration a protein relative plasma approximately for albumin, IgM while essentially no fibrinogen found this fluid. Relative concentrations are much larger small amount can be determined. This suggests that damage epidermis dermis more pronounced than blister. It shown not destroyed by Implications findings discussed.

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