Differences In High-Intensity Signal Volume Between Arterial Spin Labeling And Contrast-Enhanced T1-Weighted Imaging May Be Useful For Differentiating Glioblastoma From Brain Metastasis
作者： Mungunbagana Ganbold, MD , Masafumi Harada, MD, PhD , Delgerdalai Khashbat, MD, PhD , Takashi Abe, MD, PhD , Teruyoshi Kageji, MD, PhD
DOI: 10.2152/JMI.64.58
关键词: Blood flow 、 Arterial spin labeling 、 Contrast (vision) 、 White matter 、 Chemistry 、 Receiver operating characteristic 、 Volume (thermodynamics) 、 Brain metastasis 、 Nuclear medicine 、 Metastasis
摘要: Purpose : To determine whether differences in tumor volume between arterial spin labeling (ASL) and contrast-enhanced T1-weighted MR images (CE+T1WI) can help differentiate glioblastoma (GBM) from brain metastasis. Materials methods Patients with a diagnosis of GBM (n=25) or metastasis (n=13) were examined by both conventional ASL imaging. Volumes interest high signal intensity on CE+T1WI defined using three dimensional analysis software. Tumor difference (ASL-CE) ratio (ASL/CE) obtained. Absolute maximal blood flow (TBF) TBF (normalized to white matter) also measured. The Mann-Whitney U test receiver operating characteristic curve performed compare measurements the groups. Results Both significantly higher than for metastasis, but not significant. Conclusion as measured might be useful differentiating whereas ASL-derived is insufficient.
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