Symbionts as Major Modulators of Insect Health: Lactic Acid Bacteria and Honeybees

摘要: Lactic acid bacteria (LAB) are well recognized beneficial host-associated members of the microbiota humans and animals. Yet LAB-associations invertebrates have been poorly characterized their functions remain obscure. Here we show that honeybees possess an abundant, diverse ancient LAB in honey crop with effects for bee health, defending them against microbial threats. Our studies all extant honeybee species plus related apid bees reveal one largest collections novel from genera Lactobacillus Bifidobacterium ever discovered within a single insect suggest long (>80 mya) history association. Bee associated microbiotas highlight kunkeei as dominant member. Those showing potent antimicrobial properties acquired by callow workers nestmates maintained biofilms, though beekeeping management practices can negatively impact this microbiota. Prophylactic enhance LAB, or supplementary feeding may serve integrated approaches to sustainable pollinator service provision. We anticipate will become central on including colony collapse disorder, act exemplar case insect-microbe symbiosis.