Circulating IL-1β levels, polymorphisms of IL-1B, and risk of cervical cancer in Chinese women
作者： Nianfeng Qian , Xiaojun Chen , Suping Han , Fulin Qiang , Guangfu Jin
DOI: 10.1007/S00432-009-0710-5
关键词: Oncovirus 、 Carcinogenesis 、 Case-control study 、 Cancer 、 Single-nucleotide polymorphism 、 Immunology 、 Haplotype 、 Genotype 、 Cervical cancer 、 Medicine
摘要: Purpose Long-term human papillomavirus (HPV) infection is a prerequisite for cervical cancer. IL-1β and IL-1Ra expression levels play an important role in carcinogenesis. Several functional genetic variants IL1B IL-RN have been reported to be associated with cancer susceptibility. In the current study, we hypothesized that plasma levels, IL-1B polymorphisms were candidate biomarkers
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