A Clinical Trial of Antioxidant Vitamins to Prevent Colorectal Adenoma
作者： E. Robert Greenberg , John A. Baron , Tor D. Tosteson , Daniel H. Freeman , Gerald J. Beck
DOI: 10.1056/NEJM199407213310301
关键词: Medicine 、 Regimen 、 Colorectal adenoma 、 Adenoma 、 Carotene 、 Gastroenterology 、 Ascorbic acid 、 Randomized controlled trial 、 Vitamin E 、 Lower risk 、 Surgery 、 Internal medicine 、 General Medicine
摘要: … In 1984, we began a large clinical trial of the effects of beta carotene and the combination of … according to the size of the largest adenoma in each patient, using the Kruskal-Wallis test …
sci-hub.se 参考文章(43)
P. J. Cheek, P. McCullagh, J. A. Nelder, Generalized Linear Models, 2nd Edn. Applied Statistics. ,vol. 39, pp. 385- 386 ,(1990) , 10.2307/2347392
G McKeown-Eyssen, C Holloway, E Bright-See, V Jazmaji, P Dion, W R Bruce, A Randomized Trial of Vitamins C and E in the Prevention of Recurrence of Colorectal Polyps Cancer Research. ,vol. 48, pp. 4701- 4705 ,(1988)
Martin Lipkin, Biomarkers of increased susceptibility to gastrointestinal cancer: new application to studies of cancer prevention in human subjects. Cancer Research. ,vol. 48, pp. 235- 245 ,(1988)
Lawrence H. Kushi, Aaron R. Folsom, Kristi A. Steinmetz, John D. Potter, Roberd M. Bostick, Thomas A. Sellers, David R. McKenzie, Reduced Risk of Colon Cancer with High Intake of Vitamin E: The Iowa Women's Health Study Cancer Research. ,vol. 53, pp. 4230- 4237 ,(1993)
Kristi A. Steinmetz, John D. Potter, Vegetables, fruit, and cancer. II. Mechanisms. Cancer Causes & Control. ,vol. 2, pp. 427- 442 ,(1991) , 10.1007/BF00054304
Eric R. Fearon, Bert Vogelstein, A genetic model for colorectal tumorigenesis Cell. ,vol. 61, pp. 759- 767 ,(1990) , 10.1016/0092-8674(90)90186-I
Steven M. Powell, Nathan Zilz, Yasmin Beazer-Barclay, Tracy M. Bryan, Stanley R. Hamilton, Stephen N. Thibodeau, Bert Vogelstein, Kenneth W. Kinzler, APC mutations occur early during colorectal tumorigenesis. Nature. ,vol. 359, pp. 235- 237 ,(1992) , 10.1038/359235A0
Geert van Poppel, Carotenoids and cancer: An update with emphasis on human intervention studies European Journal of Cancer. ,vol. 29, pp. 1335- 1344 ,(1993) , 10.1016/0959-8049(93)90087-V
G. Hoff, A. Foerster, M. H. Vatn, J. Sauar, S. Larsen, Epidemiology of polyps in the rectum and colon. Recovery and evaluation of unresected polyps 2 years after detection. Scandinavian Journal of Gastroenterology. ,vol. 21, pp. 853- 862 ,(1986) , 10.3109/00365528609011130
David W. Nierenberg, Serum and plasma β-carotene levels measured with an improved method of high-performance liquid chromatography Journal of Chromatography B: Biomedical Sciences and Applications. ,vol. 339, pp. 273- 284 ,(1985) , 10.1016/S0378-4347(00)84654-X