Baseline platelet reactivity in acute myocardial infarction treated with primary angioplasty— Influence on myocardial reperfusion, left ventricular performance, and clinical events

摘要: Background Platelet reactivity is believed to play a key role in the pathophysiology of ST-segment elevation myocardial infarction (STEMI). We sought determine whether platelet predicts impaired reperfusion, left ventricular (LV) dysfunction, and clinical events an unselected group patients with STEMI. Methods was measured before primary angioplasty 125 consecutive use Function Analyzer-100. Six-month follow-up performed. Results Patients were stratified into 4 quartiles according collagen adenosine diphosphate closure time (CADP-CT), fourth quartile (CADP-CT ≤55 seconds; n=32) defined as high reactivity. There increasing rate diabetes across quartiles: 6% first 38% ( P = .0005). Conclusions independent predictor reperfusion. Moreover, CADP-CT being marker reflow may also provide early prognostic information concerning LV performance adverse after