Use of Combined Monoclonal Antibodies for the Immunochemical Determination of Apolipoproteins A–I and B in Human Plasma

作者: Santica Marcovina , Alberico L Catapano , None

DOI: 10.1007/978-1-4684-1268-0_10

关键词: Apolipoproteins AFamilial hypercholesterolemiaCholesterolEndocrinologyInternal medicineCoronary artery diseaseMedicineMonoclonal antibodyRadial immunodiffusionLipoproteinRisk factor

摘要: Plasma cholesterol level Is a risk factor for the development of coronary artery disease (1). Indeed, bound to low-density lipoprotein (LDL) appears better correlate with heart (CHD) as compared plasma levels while high-density (HDL) is inversely related developing CHD.

参考文章(14)
S. MARCOVINA, P.J. PRICE, J.S. McDOUGAL, L. CREMONESI, Monoclonal Antibodies Directed against Human Low Density Lipoprotein and Their Characterization by the Immunodot Technique Protides of the biological fluids. ,vol. 31, pp. 985- 988 ,(1984) , 10.1016/B978-0-08-030764-0.50225-1
B P Tsao, L K Curtiss, T S Edgington, Immunochemical heterogeneity of human plasma apolipoprotein B. II. Expression of apolipoprotein B epitopes on native lipoproteins. Journal of Biological Chemistry. ,vol. 257, pp. 15222- 15228 ,(1982) , 10.1016/S0021-9258(18)33416-1
S Marcovina, D France, R A Phillips, S J Mao, Monoclonal antibodies can precipitate low-density lipoprotein. I. Characterization and use in determining apolipoprotein B. Clinical Chemistry. ,vol. 31, pp. 1654- 1658 ,(1985) , 10.1093/CLINCHEM/31.10.1654
Thomas F. Whayne, Petar Alaupovic, Michael D. Curry, Elisa T. Lee, Paul S. Anderson, Eliot Schechter, Plasma apolipoprotein B and VLDL-, LDL-, and HDL-cholesterol as risk factors in the development of coronary artery disease in male patients examined by angiography. Atherosclerosis. ,vol. 39, pp. 411- 424 ,(1981) , 10.1016/0021-9150(81)90026-5
G. KÖHLER, C. MILSTEIN, Continuous cultures of fused cells secreting antibody of predefined specificity Nature. ,vol. 256, pp. 495- 497 ,(1975) , 10.1038/256495A0
Mary Ann K. Markwell, Suzanne M. Haas, L.L. Bieber, N.E. Tolbert, A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples Analytical Biochemistry. ,vol. 87, pp. 206- 210 ,(1978) , 10.1016/0003-2697(78)90586-9
Santica Marcovina, Giovanni Di Cola, Cristina Rapetto, Catherine Fievet, Veronique Clavey, Jean Charles Fruchart, Development of a radial immunodiffusion technique employing monoclonal antibodies for apolipoprotein B determination in human plasma Clinica Chimica Acta. ,vol. 147, pp. 117- 125 ,(1985) , 10.1016/0009-8981(85)90072-5
W.F. Riesen, R. Mordasini, C. Salzmann, A. Theler, H.P. Gurtner, Apoproteins and lipids as discriminators of severity of coronary heart disease Atherosclerosis. ,vol. 37, pp. 157- 162 ,(1980) , 10.1016/0021-9150(80)90104-5