Ovarian cancer: patterns of care in Victoria during 1993-1995.

作者: Marisa Grossi , Prudence A Francis , Michael A Quinn , Robert M Rome , Robert S Planner

DOI: 10.5694/J.1326-5377.2002.TB04616.X

关键词: PopulationSurgeryCarcinomaRelative survivalStage (cooking)Ovarian cancerInternal medicineRetrospective cohort studyMedicineCancer registryCohort

摘要: Objective: To describe the management of and outcomes in patients with newly diagnosed ovarian cancer during 1993, 1994 1995 Victoria. Design setting: Retrospective cohort study conducted by surveying doctors involved managing incident cases identified from population-based Victorian Cancer Registry. The survey was 1997 followed up until end 1999 to obtain at least four years follow-up data on all patients. Patients: All women invasive epithelial 1995. Main outcome measures: Reported terms staging, treatment survival. Results: Management details were obtained for 84.5% (562/665) eligible Median age diagnosis 66 (range, 22-98 years). Surgery primary therapy 77.2% (434/562). Only one three had adequate surgery, which less likely be performed general gynaecologists surgeons than gynaecological oncologists (21.3% [35/164] v 13.3% [8/60] 52% [105/202]). After surgery 78.6% (341/434) received chemotherapy, usually platinum-based regimens. overall five-year relative survival 46% treated surgically; poor related increasing age, later tumour stage, presence ascites, residual disease >2 cm poorer histological differentiation tumour. Conclusions: For optimal care a preoperative carcinoma antigen (CA)-125 assay, chest x-ray pelvic ultrasound should performed, early referral multidisciplinary unit definitive is advised. Every effort made adequately stage or debulk Women high-risk early-stage advanced considered chemotherapy.

参考文章(16)
Steven A. Rosenberg, Vincent T. DeVita, Samuel Hellman, Cancer : Principles and Practice of Oncology ,(1982)
Robert C. Young, Staging Laparotomy in Early Ovarian Cancer JAMA: The Journal of the American Medical Association. ,vol. 250, pp. 3072- 3076 ,(1983) , 10.1001/JAMA.1983.03340220040030
R. William Hunter, Neal D.E. Alexander, W. Patrick Soutter, Meta-analysis of surgery in advanced ovarian carcinoma: Ismaximum cytoreductive surgery an independent determinant of prognosis? American Journal of Obstetrics and Gynecology. ,vol. 166, pp. 504- 511 ,(1992) , 10.1016/0002-9378(92)91658-W
Larry Mcgowan, Patterns of care in carcinoma of the ovary. Cancer. ,vol. 71, pp. 628- 633 ,(2010) , 10.1002/CNCR.2820710221
Erich Burghardt, Frank Girardi, Manfred Lahousen, Karl Tamussino, Haro Stettner, Patterns of pelvic and paraaortic lymph node involvement in ovarian cancer Gynecologic Oncology. ,vol. 40, pp. 103- 106 ,(1991) , 10.1016/0090-8258(91)90099-Q
P. A. Wingo, T. Tong, S. Bolden, Cancer statistics, 1995 CA: A Cancer Journal for Clinicians. ,vol. 45, pp. 8- 30 ,(1995) , 10.3322/CANJCLIN.45.1.8
Solveig Tingulstad, Bjorn Hagen, Finn Egil Skjeldestad, Mathias Onsrud, Torvid Kiserud, Tore Halvorsen, Kjell Nustad, Evaluation of a risk of malignancy index based on serum CA125, ultrasound findings and menopausal status in the pre-operative diagnosis of pelvic masses British Journal of Obstetrics and Gynaecology. ,vol. 103, pp. 826- 831 ,(1996) , 10.1111/J.1471-0528.1996.TB09882.X
EJ Junor, DJ Hole, CR Gillis, Management of ovarian cancer: referral to a multidisciplinary team matters. British Journal of Cancer. ,vol. 70, pp. 363- 370 ,(1994) , 10.1038/BJC.1994.307
Martine J Piccart, Kamma Bertelsen, Keith James, Jim Cassidy, Constantino Mangioni, Ernst Simonsen, Gavin Stuart, Stan Kaye, Ignace Vergote, René Blom, Robert Grimshaw, Ronald J Atkinson, Ken D Swenerton, Claes Trope, Mario Nardi, Janne Kaern, Salvatore Tumolo, Petra Timmers, Josée-Anne Roy, François Lhoas, Berit Lindvall, Monica Bacon, Angelo Birt, Joern Erik Andersen, Benny Zee, James Paul, Benoît Baron, Sergio Pecorelli, Randomized Intergroup Trial of Cisplatin–Paclitaxel Versus Cisplatin–Cyclophosphamide in Women With Advanced Epithelial Ovarian Cancer: Three-Year Results Journal of the National Cancer Institute. ,vol. 92, pp. 699- 708 ,(2000) , 10.1093/JNCI/92.9.699
Scott M. Eisenkop, Nick M. Spirtos, Thomas W. Montag, Richard H. Nalick, He-Jing Wang, The impact of subspecialty training on the management of advanced ovarian cancer. Gynecologic Oncology. ,vol. 47, pp. 203- 209 ,(1992) , 10.1016/0090-8258(92)90107-T