作者: Marisa Grossi , Prudence A Francis , Michael A Quinn , Robert M Rome , Robert S Planner
DOI: 10.5694/J.1326-5377.2002.TB04616.X
关键词: Population 、 Surgery 、 Carcinoma 、 Relative survival 、 Stage (cooking) 、 Ovarian cancer 、 Internal medicine 、 Retrospective cohort study 、 Medicine 、 Cancer registry 、 Cohort
摘要: Objective: To describe the management of and outcomes in patients with newly diagnosed ovarian cancer during 1993, 1994 1995 Victoria. Design setting: Retrospective cohort study conducted by surveying doctors involved managing incident cases identified from population-based Victorian Cancer Registry. The survey was 1997 followed up until end 1999 to obtain at least four years follow-up data on all patients. Patients: All women invasive epithelial 1995. Main outcome measures: Reported terms staging, treatment survival. Results: Management details were obtained for 84.5% (562/665) eligible Median age diagnosis 66 (range, 22-98 years). Surgery primary therapy 77.2% (434/562). Only one three had adequate surgery, which less likely be performed general gynaecologists surgeons than gynaecological oncologists (21.3% [35/164] v 13.3% [8/60] 52% [105/202]). After surgery 78.6% (341/434) received chemotherapy, usually platinum-based regimens. overall five-year relative survival 46% treated surgically; poor related increasing age, later tumour stage, presence ascites, residual disease >2 cm poorer histological differentiation tumour. Conclusions: For optimal care a preoperative carcinoma antigen (CA)-125 assay, chest x-ray pelvic ultrasound should performed, early referral multidisciplinary unit definitive is advised. Every effort made adequately stage or debulk Women high-risk early-stage advanced considered chemotherapy.