Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling.
作者： M Givskov , R de Nys , M Manefield , L Gram , R Maximilien
DOI: 10.1128/JB.178.22.6618-6622.1996
关键词: Interference (genetic) 、 Bacteria 、 Biochemistry 、 Signalling 、 Intracellular 、 Lactone 、 N-Acyl homoserine lactone 、 Biology 、 Homoserine 、 Quorum Quenching
摘要: Acylated homoserine lactones (AHLs) play a widespread role in intercellular communication among bacteria. The Australian macroalga Delisea pulchra produces secondary metabolites which have structural similarities to AHL molecules. We report here that these inhibited AHL-controlled processes prokaryotes. Our results suggest the interaction between higher organisms and their surface-associated bacteria may be mediated by interference with bacterial regulatory systems.
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