Ventilatory efficiency testing as prognostic value in patients with pulmonary hypertension

摘要: Increased ventilatory response has been shown to have a high prognostic value in patients with chronic heart failure. Our aim was therefore determine the efficiency pulmonary arterial hypertension and thromboembolic by cardiopulmonary exercise testing (CPET) identifying PH-patients increased risk for death within 24 months after evaluation. 116 (age: 64 ± 1 years) mean pressure of 35 ± 1 mmHg underwent CPET right catheterization. During follow-up 24 months, we compared initial characteristics survivors (n = 87) nonsurvivors (n = 29). Significant differences (p ≤ 0.005) between existed equivalents oxygen (42.1 ± 2.1 versus 56.9 ± 2.6) carbon dioxide (Ve/VCO2) (47.5 ± 2.2 64.4 ± 2.3). Patients peak uptake ≤ 10.4 ml/min/kg had 1.5-fold, Ve/VCO2 ≥ 55 7.8-fold, alveolar-arterial difference ≥ 55 mmHg 2.9-fold, Ve/VCO2 slope ≥ 60 5.8-fold mortality next 24 months. results demonstrate that abnormalities ventilation powerfully predict outcomes PH. Consideration should be given add clinical guidelines reflect importance parameters addition VO2.