Diastolic Dysfunction in Normotensive Men with Well-Controlled Type 2 Diabetes: Importance of maneuvers in echocardiographic screening for preclinical diabetic cardiomyopathy

摘要: OBJECTIVE — Because a pseudonormal pattern of ventricular filling has never been considered in studies that reported prevalence of left ventricular diastolic dysfunction (LVDD) between 20 and 40%, our aim was to more completely evaluate the LVDD subjects with diabetes. RESEARCH DESIGN AND METHODS We studied 46 men with type 2 diabetes who were aged 38-67 years; without evidence diabetic complications, hypertension, coronary artery disease, congestive heart failure, or thyroid overt renal disease; maximal treadmill exercise test showing no ischemia. was evaluated by Doppler echocardiography, which included use Valsalva maneuver and pulmonary venous recordings to unmask left ventricular filling. RESULTS found 28 (60%), whom 13 (28%) had filling 15 (32%) had impaired relaxation. Systolic function normal all subjects, there no correlation indexes metabolic control. CONCLUSIONS is much common than previously reported in well-controlled 2 diabetes are free clinically detectable heart disease. The high this phenomenon this high-risk population suggests screening for diabetes should include procedures such as pulmonary venous recordings