Multiple smooth muscle tumors arising in deep soft tissue of lower limbs with uterine leiomyomas.

摘要: A 40-year-old woman had multiple smooth muscle tumors in the left inguinal region, bilateral thighs, omentum, peritoneum, and right infundibulum pelvic ligament associated with uterine leiomyomas. She a history of leiomyomas, which were resected 13 years ago. Histopathologic evaluation revealed tumor masses composed cells relatively low cellularity, consistent diagnosis leiomyoma. Tumor necrosis nuclear atypia absent. Mitotic figures very scarce (less than 1 mitotic figure per 10 high-power fields). Immunohistochemical positive reaction to markers, estrogen receptors, progesterone receptors. No pulmonary lesion was found. Similar instances leiomyomas histologically benign extrauterine have been reported. This curious condition has referred as "benign metastasizing leiomyoma," most reported cases involve lungs. The distribution our case is unusual may be first deep soft tissue limbs. Consideration given concept that these multifocal origin, rather metastases.