Evaluating Bone Metabolism In Asthmatic Cases Using Inhaled Steroids
作者： Secil Aydinoz , Tolga Unsur , Mustafa Gultepe , Halit Ozkaya , Ismail Gocmen
DOI:
关键词: Bone mineral 、 Asthma 、 N-terminal telopeptide 、 Internal medicine 、 Bone density 、 Hydroxyproline 、 Endocrinology 、 Prepubertal stage 、 Medicine 、 Bone remodeling 、 Pathogenesis
摘要: Background: Bronchial asthma is a chronic inflammatory disease in which eosinophils and different cells play major role pathogenesis, characterized by increased bronchial sensitivity of the airways. Topical steroids had been used to avoid long-term side effects systemic asthma. The inhaled corticosteroids may be explained combined many factors. Objective: This study was performed investigate on bone mineralization also density. Methods: Ninety-seven children divided into three groups, diagnosed with followed up 2002 2003 at GATA Haydarpasa Teaching Hospital were included study. Bone remodeling destruction markers examine metabolism. Results: Comparisons between groups among all revealed no statistical differences specific alkaline phosphatase (bALP), hydroxyproline (HP), carboxy-terminal telopeptide type1 collagen (ICTP), calcium-creatinine ratio (Ca/GF), calcium (Ca) phosphor (P) levels. Analysis that mineral density (BMD) scores significantly higher pubertal stage cases compared those prepubertal stage.
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