Ciprofloxacin resistance among nosocomial Pseudomonas aeruginosa and Staphylococcus aureus in the United States

摘要: Objective We attempted to determine if an increase in resistance ciprofloxacin occurred among nosocomial pathogens, especially Pseudomonas aeruginosa and Staphylococcus aureus. Methods examined 1989-1992 susceptibility results from 8,517 P 9,021 S aureus isolates associated with infections reported the National Nosocomial Infections Surveillance System. Results For aureus, 27.1% of were resistant ciprofloxacin; methicillin-resistant isolates, 80% also ciprofloxacin. A logistic regression model found that was more common isolated urinary respiratory tracts than other sites isolation, methicillin resistant. After controlling for these factors, showed a 123% odds 1989-1990 1991-1992. aeruginosa, 4.7% Resistance varied by site infection rose most dramatically tract 2.0% 5.3% Conclusion is frequent increasing rapidly selected isolates.