Clinically Relevant Biomarker Discovery in High-Risk Recurrent Neuroblastoma.

作者: Peter Utnes , Cecilie Løkke , Trond Flægstad , Christer Einvik

DOI: 10.1177/1176935119832910

关键词: Downregulation and upregulationNeuroblastomaCancer researchMEG3Biomarker discoveryGenePediatric cancerCell cultureMedicinemicroRNA

摘要: … Briefly, 1 µg RNA was reverse transcribed using the PTC-200 Thermal Cycler with the … A genome-wide microRNA profiling indicates miR-424-5p and miR-503-5p as regulators of …

参考文章(96)
Manrong Jiang, Jennifer Stanke, Jill M. Lahti, The connections between neural crest development and neuroblastoma. Current Topics in Developmental Biology. ,vol. 94, pp. 77- 127 ,(2011) , 10.1016/B978-0-12-380916-2.00004-8
Lidia Ruiz-Llorente, Soraya Ardila-González, Luisa F Fanjul, Olaia Martínez-Iglesias, Ana Aranda, microRNAs 424 and 503 are mediators of the anti-proliferative and anti-invasive action of the thyroid hormone receptor beta. Oncotarget. ,vol. 5, pp. 2918- 2933 ,(2014) , 10.18632/ONCOTARGET.1577
Linda M. Parysek, Linda M. Parysek, Linda M. Parysek, Susan L. Cohn, Susan L. Cohn, Susan L. Cohn, Helen R. Salwen, Helen R. Salwen, Helen R. Salwen, John Foley, Janet Cowan, Janet Cowan, Janet Cowan, Karen L. Mason, Karen L. Mason, Karen L. Mason, Daniel Chagnovich, Daniel Chagnovich, Daniel Chagnovich, Differential expression of N-myc in phenotypically distinct subclones of a human neuroblastoma cell line. Cancer Research. ,vol. 51, pp. 6338- 6345 ,(1991)
Cecilie Løkke, Christer Einvik, Peter Utnes, Bjørn Helge Haug, Trond Flægstad, Øyvind H. Hald, Sarah A. Roth, Exosome-like Extracellular Vesicles from MYCN-amplified Neuroblastoma Cells Contain Oncogenic miRNAs Anticancer Research. ,vol. 35, pp. 2521- 2530 ,(2015)
Mike Russell, Annalise Penikis, Derek Oldridge, Juan Alvarez-Dominguez, Lee McDaniel, Maura Diamond, Olivia Padovan, Pichai Raman, Yimei Li, Jun S Wei, Shile Zhang, Janahan Gnanchandran, Robert Seeger, Shahab Asgharzadeh, Javed Khan, Sharon J, Diskin, John M Maris, Kristina A Cole, CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus Cancer Research. ,vol. 75, pp. 3155- 3166 ,(2015) , 10.1158/0008-5472.CAN-14-3613
Nadia Vadie, Sheena Saayman, Alexandra Lenox, Amanda Ackley, Mathew Clemson, Jon Burdach, Jonathan Hart, Peter K Vogt, Kevin V Morris, MYCNOS functions as an antisense RNA regulating MYCN RNA Biology. ,vol. 12, pp. 893- 899 ,(2015) , 10.1080/15476286.2015.1063773
S L Cohn, C V Herst, H S Maurer, S T Rosen, N-myc amplification in an infant with stage IVS neuroblastoma. Journal of Clinical Oncology. ,vol. 5, pp. 1441- 1444 ,(1987) , 10.1200/JCO.1987.5.9.1441
André Oberthuer, Barbara Hero, Rüdiger Spitz, Frank Berthold, Matthias Fischer, The Tumor-Associated Antigen PRAME Is Universally Expressed in High-Stage Neuroblastoma and Associated with Poor Outcome Clinical Cancer Research. ,vol. 10, pp. 4307- 4313 ,(2004) , 10.1158/1078-0432.CCR-03-0813
Jochen Buechner, Jørn R. Henriksen, Bjørn Helge Haug, Ellen Tømte, Trond Flaegstad, Christer Einvik, Inhibition of mir-21, which is up-regulated during MYCN knockdown-mediated differentiation, does not prevent differentiation of neuroblastoma cells Differentiation. ,vol. 81, pp. 25- 34 ,(2011) , 10.1016/J.DIFF.2010.09.184
J Buechner, E Tømte, B H Haug, J R Henriksen, C Løkke, T Flægstad, C Einvik, Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN -amplified neuroblastoma British Journal of Cancer. ,vol. 105, pp. 296- 303 ,(2011) , 10.1038/BJC.2011.220