The effects of topical and intravenous JM-1232(-) on cerebral pial microvessels of rabbits

作者: Kodai Ikemoto , Tadahiko Ishiyama , Noriyuki Shintani , Nobumasa Asano , Daniel I Sessler

DOI: 10.1186/S12871-015-0016-X

关键词: AnesthesiaCerebral microcirculationCranial windowPia materReceptorHypocapniaSevofluraneHypercapniaMedicinePharmacology

摘要: Background JM-1232(-) is a novel anesthetic agent which acts through gamma-aminobutyric acid receptors. Cerebral pial vascular effects of JM-1232(-) are unknown. We thus evaluated topical and intravenous on cerebral microvessels in rabbits, the extent to carbon dioxide (CO2) reactivity preserved.

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