The action of amoebicidal drugs on Entamoeba invadens Rodhain, 1934 in vitro

作者: Elspeth W. McConnachie

DOI: 10.1017/S0031182000018849

关键词: EmetineIn vitroEntamoeba invadensBacterium coliBiologyMicrobiology

摘要: 1. A method, based on that devised for E. histolytica by Dobell (1947), was worked out testing the action of drugs upon invadens . 2. The sensitivity di- and monobacterial strains to emetine determined, a dibacterial strain quinaldines 352, 356 404. killed at concentrations 1/50,000–1/100,000, 352 or 1/100,000, 404 1/10,000. used in present tests are thus less sensitive than is , but two species similar. 3. which maintained 9 months presence increasing emetine, did not become resistant drug. I am indebted Dr A. Bishop much advice criticism; J. D. Fulton culture Bacterium coli A'; Walker supplies compounds A404. work has been financed Medical Research Council.

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