作者: Alan R. Lehmann
DOI: 10.1016/J.DNAREP.2004.07.009
关键词: G2-M DNA damage checkpoint 、 SMC protein 、 Condensin 、 Genetics 、 Kinetochore 、 Homology directed repair 、 DNA repair 、 Establishment of sister chromatid cohesion 、 Biology 、 Cohesin 、 Cell biology 、 Biochemistry 、 Molecular biology
摘要: The SMC proteins form the cores of three protein complexes in eukaryotes, cohesin, condensin and Smc5-6 complex. Cohesin holds sister chromatids together after DNA replication is involved both repair double-strand breaks by homologous recombination intra-S-phase checkpoint. Condensin assists condensation chromosomes at mitosis also has a role checkpoint control pathways. complex variety damage response pathways as yet unknown mechanisms, but associated with recombination.