Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

作者: Jurgen A. Marteijn , Simon Bekker-Jensen , Niels Mailand , Hannes Lans , Petra Schwertman

DOI: 10.1083/JCB.200902150

关键词: ChromatinDNA damageHistoneNucleotide excision repairDNA repairHistone H2A ubiquitinationBiologyMDC1Ubiquitin-conjugating enzymeMolecular biology

摘要: … excision repair (NER)–dependent histone H2A ubiquitination at sites of ultraviolet (UV)-… H2A ubiquitination at damaged DNA, which requires dynamic ubiquitination by Ubc13 and RNF8…

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