Cortical control of gait in healthy humans: an fMRI study

作者: ChiHong Wang , YauYau Wai , BoCheng Kuo , Yei-Yu Yeh , JiunJie Wang

DOI: 10.1007/S00702-008-0058-Z

关键词: Motor imagerySupplementary motor areaPsychologyPrecuneusAuditory imageryFunctional magnetic resonance imagingNeuroscienceMirror neuronPremotor cortexPrecentral gyrusPhysical medicine and rehabilitation

摘要: This study examined the cortical control of gait in healthy humans using functional magnetic resonance imaging (fMRI). Two block-designed fMRI sessions were conducted during motor imagery a locomotor-related task. Subjects watched video clip that showed an actor standing and walking egocentric perspective. In session, additional images collected when participants observed clutch movement right hand. keeping with previous studies SPECT NIRS, we detected activation many motor-related areas including supplementary area, bilateral precentral gyrus, left dorsal premotor cortex, cingulate area. Smaller activations precuneus, thalamus, part putamen. Based on these findings, propose novel paradigm to fMRI. Specifically, task used this study—involving both mirror neurons mental imagery—provides new feasible model be neuroimaging area research.

参考文章(59)
Mark Rayport, Pierre Tournoux, J. Talairach, Co-planar stereotaxic atlas of the human brain : 3-dimensional proportional system : an approach to cerebral imaging Published in <b>1988</b> in Stuttgart by Thieme. ,(1988)
Robert Iansek, Frances E. Huxham, Meg E. Morris, Noor H. Ismail, Margaret Bruce, Frontal gait apraxia. Pathophysiological mechanisms and rehabilitation. Advances in Neurology. ,vol. 87, pp. 363- 374 ,(2001)
S Kiebel, K Friston, J Ashburner, T Nichols, W Penny, Statistical Parametric Mapping: The Analysis of Functional Brain Images (2007). ,(2007)
Laila Craighero, Giorgio Metta, Giulio Sandini, Luciano Fadiga, The mirror-neurons system: data and models Progress in Brain Research. ,vol. 164, pp. 39- 59 ,(2007) , 10.1016/S0079-6123(07)64003-5
James Ashe, Ovidiu V Lungu, Alexandra T Basford, Xiaofeng Lu, Cortical control of motor sequences. Current Opinion in Neurobiology. ,vol. 16, pp. 213- 221 ,(2006) , 10.1016/J.CONB.2006.03.008
G. Buccino, F. Binkofski, G. R. Fink, L. Fadiga, L. Fogassi, V. Gallese, R. J. Seitz, K. Zilles, G. Rizzolatti, H.-J. Freund, Action observation activates premotor and parietal areas in a somatotopic manner: an fMRI study. European Journal of Neuroscience. ,vol. 13, pp. 400- 404 ,(2001) , 10.1046/J.1460-9568.2001.01385.X
Hidenao Fukuyama, Yasuomi Ouchi, Shigeru Matsuzaki, Yasuhiro Nagahama, Hiroshi Yamauchi, Masafumi Ogawa, Jun Kimura, Hiroshi Shibasaki, Brain functional activity during gait in normal subjects: a SPECT study Neuroscience Letters. ,vol. 228, pp. 183- 186 ,(1997) , 10.1016/S0304-3940(97)00381-9
Marco Iacoboni, John C. Mazziotta, Mirror neuron system: basic findings and clinical applications. Annals of Neurology. ,vol. 62, pp. 213- 218 ,(2007) , 10.1002/ANA.21198
M. Bakker, C. C. P. Verstappen, B. R. Bloem, I. Toni, Recent advances in functional neuroimaging of gait Journal of Neural Transmission. ,vol. 114, pp. 1323- 1331 ,(2007) , 10.1007/S00702-007-0783-8