Choroidal Structure after Half-Dose Photodynamic Therapy in Chronic Central Serous Chorioretinopathy.

摘要: The study aims to analyze the changes produced by half-dose photodynamic therapy (HD-PDT) in choroid of eyes with chronic central serous chorioretinopathy (CSC) applying binarization method spectral domain optical coherence tomography (SDOCT) and OCT Angiography (OCTA) images. SDOCT OCTA were performed before, one hour, week, month after HD-PDT. Binarization a modified Niblack analysis ImageJ applied. An average ratio between luminal part total structure was calculated. Twenty-two 21 patients (20 male 1 female; mean age 54.8 years) enrolled. A statistically significant reduction choroidal thickness observed week (from 407 µm 362 µm, p = 0.034) 341.5 0.0004) baseline 33.4% SDOCT, 61.1% OCTA. These values 35.3% 61% 33.9% 60.4% 34.5% 60.6% HD-PDT, respectively. Overall, PDT seems produce short-term on component both choriocapillaris choroid, which return status from treatment. However, stays significantly thinner month, interstitial components reduced.