The Riddle of Nonalcoholic Fatty Liver Disease: Progression From Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis
作者： Mithun Sharma , Shasikala Mitnala , Ravi K Vishnubhotla , Rathin Mukherjee , Duvvur N Reddy
DOI: 10.1016/J.JCEH.2015.02.002
关键词: Adiponectin 、 Internal medicine 、 Lipotoxicity 、 Saturated fatty acid 、 Medicine 、 Nonalcoholic fatty liver disease 、 Fatty liver 、 Gut flora 、 Cirrhosis 、 Polyunsaturated fatty acid 、 Endocrinology 、 Bioinformatics
摘要: Nonalcoholic fatty liver (NAFL) is an emerging global epidemic which progresses to nonalcoholic steatohepatitis (NASH) and cirrhosis in a subset of subjects. Various reviews have focused on the etiology, epidemiology, pathogenesis treatment NAFLD. This review highlights specifically triggers implicated disease progression from NAFL NASH. The integrating role genes, dietary factors, innate immunity, cytokines gut microbiome been discussed.
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