Nitrogen-functionalized graphene oxide as thermally stable bioscaffold

作者: Gopal Avashthi , Shrikant S. Maktedar , Man Singh

DOI: 10.1063/5.0001724

关键词: Thermal stabilityThermogravimetric analysisFourier transform infrared spectroscopyMaterials scienceNuclear chemistryInfrared spectroscopyGrapheneAbsorption spectroscopyOxideX-ray photoelectron spectroscopy

摘要: Sonochemical method has been used for graphene oxide functionalization (f-GrO). The acoustic cavitation acts as a small reactor to induce in-situ temperature (T) GrO with 5-Amino-1,3,4-thiadiazole-2-thiol (ATDT) [f-(ATDT)GrO] nitrogen functionalized (N-f-GrO). thermal stability (TS) of N-f-GrO was confirmed using thermogravimetric analysis (TGA) total % wt. loss 51.7 at 231.8 °C. establishment new electronic entities in X-ray photoelectron spectroscopy (XPS), Soft absorption (SXAS), diffraction (XRD). characteristics functional groups were Fourier-transform infrared (FTIR) and 13C solid-state NMR (SSNMR). Insight structural cell viabilities 10-80 µg/ml on MCF-7 Vero lines observed average values 98.02 88.65 respectively Sulforhodamine B (SRB) assay.

参考文章(11)
A. K. Geim, K. S. Novoselov, The rise of graphene Nature Materials. ,vol. 6, pp. 183- 191 ,(2007) , 10.1038/NMAT1849
Daniela C. Marcano, Dmitry V. Kosynkin, Jacob M. Berlin, Alexander Sinitskii, Zhengzong Sun, Alexander Slesarev, Lawrence B. Alemany, Wei Lu, James M. Tour, Improved Synthesis of Graphene Oxide ACS Nano. ,vol. 4, pp. 4806- 4814 ,(2010) , 10.1021/NN1006368
Vasilios Georgakilas, Michal Otyepka, Athanasios B. Bourlinos, Vimlesh Chandra, Namdong Kim, K. Christian Kemp, Pavel Hobza, Radek Zboril, Kwang S. Kim, Functionalization of Graphene: Covalent and Non-Covalent Approaches, Derivatives and Applications Chemical Reviews. ,vol. 112, pp. 6156- 6214 ,(2012) , 10.1021/CR3000412
Malgorzata Wojtoniszak, Xuecheng Chen, Ryszard J. Kalenczuk, Anna Wajda, Joanna Łapczuk, Mateusz Kurzewski, Marek Drozdzik, Pual K. Chu, Ewa Borowiak-Palen, Synthesis, dispersion, and cytocompatibility of graphene oxide and reduced graphene oxide Colloids and Surfaces B: Biointerfaces. ,vol. 89, pp. 79- 85 ,(2012) , 10.1016/J.COLSURFB.2011.08.026
Deepa Suhag, Arun Kumar Sharma, Pranav Patni, Sandeep Kumar Garg, Satyendra K. Rajput, Sandip Chakrabarti, Monalisa Mukherjee, Hydrothermally functionalized biocompatible nitrogen doped graphene nanosheet based biomimetic platforms for nitric oxide detection Journal of Materials Chemistry B. ,vol. 4, pp. 4780- 4789 ,(2016) , 10.1039/C6TB01150K
A. Francis, R. Detsch, A.R. Boccaccini, Fabrication and cytotoxicity assessment of novel polysiloxane/bioactive glass films for biomedical applications Ceramics International. ,vol. 42, pp. 15442- 15448 ,(2016) , 10.1016/J.CERAMINT.2016.06.195
Shrikant S. Maktedar, Gopal Avashthi, Man Singh, Understanding the significance of O-doped graphene towards biomedical applications RSC Advances. ,vol. 6, pp. 114264- 114275 ,(2016) , 10.1039/C6RA23416J
J. Ureña, S. Tsipas, A. Jiménez-Morales, E. Gordo, R. Detsch, A.R. Boccaccini, In-vitro study of the bioactivity and cytotoxicity response of Ti surfaces modified by Nb and Mo diffusion treatments Surface & Coatings Technology. ,vol. 335, pp. 148- 158 ,(2018) , 10.1016/J.SURFCOAT.2017.12.009
Xun Huang, Jiexiang He, Kai Sun, Yuanfeng Chen, Zhengang Zha, Changren Zhou, Liquid crystal behavior and cytocompatibility of graphene oxide dispersed in sodium alginate solutions Carbon. ,vol. 129, pp. 258- 269 ,(2018) , 10.1016/J.CARBON.2017.12.006
Ahruem Baek, Yu Mi Baek, Hyung-Mo Kim, Bong-Hyun Jun, Dong-Eun Kim, Polyethylene Glycol-Engrafted Graphene Oxide as Biocompatible Materials for Peptide Nucleic Acid Delivery into Cells Bioconjugate Chemistry. ,vol. 29, pp. 528- 537 ,(2018) , 10.1021/ACS.BIOCONJCHEM.8B00025