The TODAY Study: An NIH Perspective on Its Implications for Research

摘要: Once referred to as adult-onset diabetes, type 2 diabetes (T2D) has emerged in youth a consequence of the worldwide increase obesity. The development T2D among young individuals significant public health consequences these are likely manifest complications including retinopathy, nephropathy, neuropathy, and cardiovascular disease, at time that should be most active productive their lives. In response emergence mid-1990s, National Institute Diabetes Digestive Kidney Diseases (NIDDK) Institutes Health sought foster research understand address this threat. Since our knowledge about epidemiology pediatric population was based on small clinic-based reports, NIDDK partnered with Centers for Disease Control Prevention (CDC) establish SEARCH Youth Study provide population-based statistics U.S. (1). data from 2002–2003 indicated approximately 3,700 were being diagnosed annually (2). is rarely seen children younger than 10 years. In non-Hispanic white 10–19 years age, represents 15% new cases diabetes. However, predominates 10- 19-year-old minority youth, representing 86% American Indians, 70% Asian/Pacific Islanders, 58% blacks, 46% Hispanics. continuing ascertain incidence poised critical information trends both 1 youth. also described great detail characteristics T2D. Perhaps greatest concern 27% enrolled …