Cancer Research Campaign phase II trial of temozolomide in metastatic melanoma.
作者： N M Bleehen , E S Newlands , S M Lee , N Thatcher , P Selby
DOI: 10.1200/JCO.1995.13.4.910
关键词: Chemotherapy 、 Temozolomide 、 Phases of clinical research 、 Dacarbazine 、 Clinical trial 、 Survival rate 、 Toxicity 、 Medicine 、 Surgery 、 Internal medicine 、 Interferon alfa 、 Gastroenterology
摘要: … Temozolomide in the schedule used has as good activity in chemotherapy-naive metastatic melanoma as the other most active agents currently in use. Further studies of the drug on its …
openrepository.com
sci-hub.se 参考文章(19)
Kurt W. Kohn, William B. Mattes, John A. Hartley, Neil W. Gibson, DNA Sequence Selectivity of Guanine-N7 Alkylation by Three Antitumor Chloroethylating Agents Cancer Research. ,vol. 46, pp. 1943- 1947 ,(1986)
Jordan Gutterman, Giora Mavligit, Carlos S. Vallejos, Jeffrey A. Gottlieb, James K. Luce, James K. Luce, M. Andrew Burgess, Lawrence H. Einhorn, Emil J. Freireich, Evan M. Hersh, Gerald P. Bodey, Emil Frei, Prognostic Correlations and Response to Treatment in Advanced Metastatic Malignant Melanoma Cancer Research. ,vol. 34, pp. 1995- 2004 ,(1974)
Anthony E. Pegg, M. Eileen Dolan, Robert C. Moschel, Christine Mummert, R. Brian Mitchell, Effect of O6-Benzylguanine Analogues on Sensitivity of Human Tumor Cells to the Cytotoxic Effects of Alkylating Agents Cancer Research. ,vol. 51, pp. 3367- 3372 ,(1991)
Christian Fizames, François Lavelle, John A. Slack, David Chubb, John A. Hickman, Robert Stone, Simon P. Langdon, Colin Goddard, Ghousia Baig, Neil W. Gibson, Edward Lunt, Christopher Newton, Malcolm F. G. Stevens, Lisa Vickers, Antitumor Activity and Pharmacokinetics in Mice of 8-Carbamoyl-3-methyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a Novel Drug with Potential as an Alternative to Dacarbazine Cancer Research. ,vol. 47, pp. 5846- 5852 ,(1987)
Cary A. Presant, Alfred A. Bartolucci, Richard V. Smalley, W. Ralph Vogler, , Cyclophosphamide plus 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide (DTIC) with or withoutcorynebacterium parvum in metastatic malignant melanoma Cancer. ,vol. 44, pp. 899- 905 ,(1979) , 10.1002/1097-0142(197909)44:3<899::AID-CNCR2820440317>3.0.CO;2-Y
SM Lee, N Thatcher, D Crowther, GP Margison, Inactivation of O6-alkylguanine-DNA alkyltransferase in human peripheral blood mononuclear cells by temozolomide. British Journal of Cancer. ,vol. 69, pp. 452- 456 ,(1994) , 10.1038/BJC.1994.82
S Gundersen, S Aamdal, Ø Fodstad, Mitozolomide (NSC 353451), a new active drug in the treatment of malignant melanoma. Phase II trial in patients with advanced disease. British Journal of Cancer. ,vol. 55, pp. 433- 435 ,(1987) , 10.1038/BJC.1987.85
NH Mulder, WTA van der Graaf, PHB Willemse, HS Koops, EGE de Vries, DT Sleijfer, Dacarbazine (DTIC)-based chemotherapy or chemoimmunotherapy of patients with disseminated malignant melanoma. British Journal of Cancer. ,vol. 70, pp. 681- 683 ,(1994) , 10.1038/BJC.1994.372
Siow Ming Lee, Nick Thatcher, Derek Crowther, Geoffrey P Margison, In vivo depletion of O6-alkylguanine-DNA-alkyltransferase in lymphocytes and melanoma of patients treated with CB 10-277, a new DTIC analogue Cancer Chemotherapy and Pharmacology. ,vol. 31, pp. 240- 246 ,(1992) , 10.1007/BF00685554
P Herait, Ph Rougier, J Oliveira, FM Delgado, F May-Levin, M Hayat, JP Armand, None, Phase II study of mitozolomide (M & B 39,565) in colorectal and breast cancer. Investigational New Drugs. ,vol. 6, pp. 323- ,(1988) , 10.1007/BF00173652