Colorimetric and electrochemical sensing of As(III) using calix[4]pyrrole capped gold nanoparticles and evaluation of its cytotoxic activity

摘要: In the present study, for first time, calixarene stabilized nanoparticles has been exploited selective detection of As(III) in aqueous media. Calix[4]pyrrole tetrahydrazide gold synthesized without use any external reducing agent. The non-covalent interactions calix[4]pyrrole molecules on surface are demonstrated by molecular dynamics studies. have characterized using Transmission electron microscopy, Fourier-transform infrared spectroscopy, X-ray photoelectron Dynamic light scattering and zeta potential techniques. capping around its interaction with colour change from pink to blue, red shift broadening SPR band decrease discussed. also used electrochemical sensing As(III), where amperometric response upto limit 1 ppb achieved. Energy dispersive spectra data confirms presence associated nanoaprticles. It is fascinated note that capped act as a colorimetric sensor environmentally relevant anions, including NO3−, Cl−, PO43− SO42− ions. study shows inhibited proliferation cancer cell line, MCF-7 which suggests application cytotoxic