Hypophosphatemia and its clinical implications in critically ill children: A retrospective study

作者: Omer Kilic , Demet Demirkol , Raif Ucsel , Agop Citak , Metin Karabocuoglu

DOI: 10.1016/J.JCRC.2012.03.005

关键词: Pediatric intensive care unitHypophosphatemiaPediatricsSepsisEnteral administrationMedicineMechanical ventilationRetrospective cohort studyComorbidityIntensive care unit

摘要: Abstract Purpose The aims of this study were to determine the prevalence hypophosphatemia and discuss clinical implications in critically ill children. Materials Methods A retrospective review medical records children admitted pediatric intensive care unit from December 2006 2007 was conducted. Results In 60.2% (n = 71) patients, any serum phosphorous level at admission third day or seventh after hypophosphatemic range. Sepsis present 22.9% 27) studied associated with ( P .02). Hypophosphatemia also use furosemide .04), steroid β 2 agonist .026), an H blocker .004). There a significant association between rate attain target caloric requirements by enteral route .007). median time 2.9 ± 1.9 (0.2-10) days normophosphatemic group 4.4 2.8 (0.3-12) group. multiple regression model, solely demonstrated independent .006; .27; 95% confidence interval, 0.02-0.09). Significant found duration mechanical ventilation length stay .02 .001, respectively). Conclusions Critically patients are prone hypophosphatemia, especially if they cannot be fed early route. is increased unit, suggesting that active repletion might improve these parameters.

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