Microbial reduction of ω-bromoacetophenones in the presence of surfactants
作者： A Goswami , R.L Bezbaruah , J Goswami , N Borthakur , D Dey
DOI: 10.1016/S0957-4166(00)00341-4
关键词: Whole cell 、 Nanotechnology 、 Ethanol 、 Enantiomer 、 Nuclear chemistry 、 Aqueous medium 、 Chemistry 、 Reduction (complexity) 、 Pulmonary surfactant 、 Inert gas
摘要: Abstract Several ω-bromoacetophenone derivatives 6a – f were reduced to ( R )-(−)-2-bromo-1-(phenyl/substituted phenyl) ethanol 7a with whole cell biocatalysts in good yields. The enantiomeric excesses increased 95% using an anionic surfactant under inert atmosphere aqueous medium.
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