作者: EDGAR T. JAEGGI , MARK K. FRIEDBERG
DOI: 10.1111/J.1540-8159.2008.00957.X
关键词: Atrioventricular block 、 Gestation 、 Cardiac output 、 Pregnancy 、 Dexamethasone 、 Medicine 、 Anesthesia 、 Transplacental 、 Persistent Fetal Bradycardia 、 Fetus
摘要: Complete atrioventricular block (CAVB) is the most common cause of persistent fetal bradycardia. In presence a structurally normal heart, it develops primarily in anti-Ro and anti-La positive antibody pregnancies after 20 weeks gestation. There significant risk perinatal demise, particularly association with hydrops, poor ventricular function, heart rates < 55 beats/min. Transplacental treatment strategies are aimed at preventing or modulating these factors. Maternal administration dexamethasone to mitigate prevent concomitant myocardial inflammation, combination beta-stimulation for bradycardia beats/min increase cardiac output, has resulted significantly improved neonatal outcomes without reversing CAVB.