Complete Pathological Response after Sequential Therapy with Sunitinib and Radiotherapy for Metastatic Clear Cell Renal Carcinoma

摘要: Despite great improvements in the management of metastatic clear cell renal carcinoma, complete responses with antiangiogenic therapies are infrequent and pathological remain anecdotal. We report response a solitary bone metastasis from carcinoma after sequential treatment sunitinib radiotherapy. In February 2009, female patient was diagnosed left kidney, bearing only one site localized proximal extremity tibia. Radical nephrectomy performed at first. Thereafter, administered standard dose level for four weeks followed by two free each cycle. The underwent palliative radiotherapy between fifth sixth Due to stable status, radical surgery knee then analysis concluded response. This case highlights potential synergy radiation therapy carcinoma. Antiangiogenic targeted have demonstrated