Oxidation-responsive Eu2+/3+-liposomal contrast agent for dual-mode magnetic resonance imaging

作者: Levi A. Ekanger , Meser M. Ali , Matthew J. Allen

DOI: 10.1039/C4CC07027E

关键词: Positive contrastNuclear magnetic resonanceContrast (vision)LiposomeEuropiumChemistryChemical exchangeMagnetic resonance imagingDual modeSaturation transfer

摘要: An oxidation-responsive contrast agent for magnetic resonance imaging was synthesized using Eu2+ and liposomes. Positive enhancement observed with Eu2+, chemical exchange saturation transfer before after oxidation of Eu2+. Orthogonal detection modes render the concentration Eu inconsequential to molecular information provided through imaging.

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