Ouabain – the insulin of the heart

作者: H. Fürstenwerth

DOI: 10.1111/J.1742-1241.2010.02395.X

关键词: Heart failurePharmacologyAngiotensin receptorAngiotensin-converting enzymeInotropeAldosterone Receptor AntagonistEndocrinologyHeart diseaseInsulinMedicineInternal medicineAngiotensin II receptor type 1

摘要: Today, medical therapies for heart disease are based on a diverse range of drugs. Angiotensin converting enzyme inhibitors, angiotensin II receptor antagonists, β-adrenergic aldosterone as well diuretics, and inotropic agents improve clinical symptoms slow the progression contractile dysfunction. Despite these therapeutic advances, failure is still associated with an annual mortality rate 10% (1). The search better treatments optimisation existing ones remain major challenges in cardiology.

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