作者: FRANK FENNER , R.V. BLANDEN
DOI: 10.1016/B978-0-12-522050-7.50005-8
关键词: Virology 、 Biology 、 Dengue fever 、 Immune system 、 Antibody 、 Viral pathogenesis 、 Immunology 、 Vaccination 、 Viremia 、 Incubation period 、 Complement fixation test
摘要: Publisher Summary This chapter presents the history of viral immunology. The use components for vaccination has been subject experimental clinical trials with adenoviruses and influenza subunit vaccines are in current use. effect production antibodies against during course infection is vivo complement fixation, demonstrable practice by developing anti-complementary activity serum. Other antibody reactions, which may or not result neutralization infectivity, play an important role lesions, especially certain persistent infections. Immune complexes antigens rather than virions involved also pathogenesis some acute infections, such as hemorrhagic dengue glomerulonephritis found several chronic Indeed, antigenemia early formation immune complexes, viremia such, provide pathogenetic basis fever symptoms that mark end incubation period many generalized infections prodromal rash have a similar explanation.