Therapeutic targeting of gastrointestinal cancer stem cells.
作者： Jonathan Stem , John C Flickinger , Dante Merlino , Ellen M Caparosa , Adam E Snook
关键词: Gastrointestinal cancer 、 Cancer research 、 Cancer stem cell 、 Stem cell 、 Cancer 、 Medicine 、 Cancer cell 、 Metastasis 、 Disease 、 Immunotherapy
摘要: Gastrointestinal cancers remain a tremendous burden on society. Despite advances in therapy options, including chemotherapy and radiation, cancer mortality from recurrences metastases occur frequently. Cancer stem cells (CSCs) drive disease recurrence metastasis, as these are uniquely equipped to self-renew evade therapy. Therefore, eradication requires treatment strategies that target CSCs addition differentiated cells. This review highlights current literature therapies targeting gastrointestinal cancer.
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