[News methods for second trimester screening of Down syndrome: statistical analysis of the use of nasal bone length and prenasal thickness].

作者: Károly Szili , Andrea Szabó , Melinda Vanya , György Bártfai , János Szabó

DOI: 10.1556/OH.2014.29991

关键词: Prenatal screeningMass screeningDown syndromeSecond trimester screeningPregnancyNasal boneStatistical analysisMedicineGestational ageGynecology

摘要: Bevezetes: A magzati orrcsonthosszusag es a praenasalis lagyreszvastagsag merese Down-szindroma ultrahangszűresere kidolgozott modszer. Celkitűzes: szerzők celja az orrcsonthossz mereseinek ertekelesehez szukseges helyi normogram letrehozasa, illetve legmegfelelőbb statisztikai modszer kivalasztasa. Modszer: Euploid (n = 1500) 21-es triszomias 10) magzatokban vegeztek vizsgalatot 2008. aprilis 2013. december kozott. Az lagyreszvastagsag-merest Medisono Anyai Magzati Egeszsegkozpontban, citogenetikai Szegedi Tudomanyegyetem Orvosi Genetikai Intezeteben vegeztek. Normogramokat keszitettek kulonboző szamu magzatokon 100, 300, 500, 750, 1000 3 analizissel (box-plot analizis, linearisregresszio- szigmoidregresszio-elemzes). Eredmenyek: Eredmenyeik alapjan megbizhato normogramok keszitesehez legalabb gravida meresi adatara van szukseg. nagyobb esetszam előnyosen ...

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