作者: Raquel Mesquita Ribeiro , Cristina Ribeiro-Silva , Gabriel G. Martins , Valeria Matranga , Arjen Scholten
DOI: 10.1016/J.DIB.2016.04.002
关键词: Proteome 、 Nectin 、 Quantitative proteomics 、 Biology 、 Exocytosis 、 Sea urchin 、 Paracentrotus lividus 、 Adhesive 、 Tube feet 、 Cell biology 、 Botany
摘要: Sea urchins have specialized adhesive organs called tube feet, which mediate strong but reversible adhesion. Tube feet are composed by a disc, producing and de-adhesive secretions for substratum attachment, stem movement. After detachment the secreted remains bound to as footprint. Recently, label-free quantitative proteomic approach coupled with latest mass-spectrometry technology was used analyze differential proteome of Paracentrotus lividus organ, comparing protein expression levels in part (the disc) versus non-adhesive stem), also profile (glue). This data article contains complementary figures results related research "Deciphering molecular mechanisms underlying sea urchin adhesion: proteomics approach" (Lebesgue et al., 2016) [1]. Here we provide dataset 1384 non-redundant proteins, their fragmented peptides levels, resultant from analysis proteome. Of these, 163 highly over-expressed disc proteins (>3-fold), likely representing most relevant adhesion, were further annotated order determine potential functions. In addition, 611 identified proteome, well functional annotation grouping 5 major groups exocytosis, microbial protection. list analyzed identify abundant pinpoint putative such Nectin, glue. The obtained uncover key involved step forward development new wet-effective bio-inspired adhesives.