Phocine Distemper in a Harp Seal (Phoca groenlandica) from the Gulf of St. Lawrence, Canada

摘要: The first case of phocine distemper in a seal from Canadian waters and the clinical harp seal, Phoca groenlandica, is reported. A two-month-old female stranded on Prince Edward Island May 1991. Significant findings were lethargy severe conjunctivitis. Pulmonary congestion was main necropsy finding, histological lesions included diffuse demyelinating nonsuppurative encephalitis mild multifocal interstitial pneumonia. Acidophilic intracytoplasmic intranuclear inclusions present cerebral neurons astrocytes. Immunoperoxidase staining confirmed virus (PDV) antigen cytoplasm nuclei neurons, bronchiolar gland epithelium transitional bladder. Infectivity titers canine di;-temper (CDV) (Onderstpoort strain) morbillivirus isolated grey significantly reduced by serum seal.