SPring-8 synchrotron radiation imaging for analyzing cardiovascular function in anesthetized small animals.

Takahiro Higuchi, Shigeru Miyagawa, James T. Pearson, Satsuki Fukushima, Atsuhiro Saito, Hirotsugu Tsuchimochi, Takashi Sonobe, Yutaka Fujii, Naoto Yagi, Alberto Astolfo, Mikiyasu Shirai, Yoshiki Sawa, Functional and Electrical Integration of Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Myocardial Infarction Rat Heart. Cell Transplantation. ,vol. 24, pp. 2479- 2489 ,(2015) , 10.3727/096368914X685799

Hisashi Nagai, Ichiro Kuwahira, Daryl O. Schwenke, Hirotsugu Tsuchimochi, Akina Nara, Sayoko Ogura, Takashi Sonobe, Tadakatsu Inagaki, Yutaka Fujii, Rutsuko Yamaguchi, Lisa Wingenfeld, Keiji Umetani, Tatsuo Shimosawa, Ken-ichi Yoshida, Koichi Uemura, James T. Pearson, Mikiyasu Shirai, Pulmonary Macrophages Attenuate Hypoxic Pulmonary Vasoconstriction via β3AR/iNOS Pathway in Rats Exposed to Chronic Intermittent Hypoxia PLOS ONE. ,vol. 10, pp. e0131923- ,(2015) , 10.1371/JOURNAL.PONE.0131923

Takashi Sonobe, Hirotsugu Tsuchimochi, Daryl O. Schwenke, James T. Pearson, Mikiyasu Shirai, Treadmill running improves hindlimb arteriolar endothelial function in type 1 diabetic mice as visualized by X-ray microangiography. Cardiovascular Diabetology. ,vol. 14, pp. 51- 51 ,(2015) , 10.1186/S12933-015-0217-0

Mark T Waddingham, Amanda J Edgley, Alberto Astolfo, Tadakatsu Inagaki, Yutaka Fujii, Cheng-Kun Du, Dong-Yun Zhan, Hirotsugu Tsuchimochi, Naoto Yagi, Darren J Kelly, Mikiyasu Shirai, James T Pearson, Chronic Rho-kinase inhibition improves left ventricular contractile dysfunction in early type-1 diabetes by increasing myosin cross-bridge extension Cardiovascular Diabetology. ,vol. 14, pp. 92- 92 ,(2015) , 10.1186/S12933-015-0256-6

Mathew J. Jenkins, Amanda J. Edgley, Takashi Sonobe, Keiji Umetani, Daryl O. Schwenke, Yutaka Fujii, Russell D. Brown, Darren J. Kelly, Mikiyasu Shirai, James T. Pearson, Dynamic Synchrotron Imaging of Diabetic Rat Coronary Microcirculation In Vivo Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 32, pp. 370- 377 ,(2012) , 10.1161/ATVBAHA.111.237172

K Matsukawa, T Shindo, M Shirai, I Ninomiya, Direct observations of sympathetic cholinergic vasodilatation of skeletal muscle small arteries in the cat. The Journal of Physiology. ,vol. 500, pp. 213- 225 ,(1997) , 10.1113/JPHYSIOL.1997.SP022011

James T Pearson, Mikiyasu Shirai, Daryl O Schwenke, Gabriela A Eppel, Roger G Evans, Amanda J Edgley, Hirotsugu Tsuchimochi, Keiji Umetani, SYNCHROTRON-BASED ANGIOGRAPHY FOR INVESTIGATION OF THE REGULATION OF VASOMOTOR FUNCTION IN THE MICROCIRCULATION IN VIVO Clinical and Experimental Pharmacology and Physiology. ,vol. 36, pp. 107- 116 ,(2009) , 10.1111/J.1440-1681.2008.05073.X

Mathew J. Jenkins, James T. Pearson, Daryl O. Schwenke, Amanda J. Edgley, Takashi Sonobe, Yutaka Fujii, Hatsue Ishibashi-Ueda, Darren J. Kelly, Naoto Yagi, Mikiyasu Shirai, Myosin heads are displaced from actin filaments in the in situ beating rat heart in early diabetes. Biophysical Journal. ,vol. 104, pp. 1065- 1072 ,(2013) , 10.1016/J.BPJ.2013.01.037

Mikiyasu Shirai, Hirotsugu Tsuchimochi, Hisashi Nagai, Emily Gray, James T. Pearson, Takashi Sonobe, Misa Yoshimoto, Tadakatsu Inagaki, Yutaka Fujii, Keiji Umetani, Ichiro Kuwahira, Daryl O. Schwenke, Pulmonary vascular tone is dependent on the central modulation of sympathetic nerve activity following chronic intermittent hypoxia Basic Research in Cardiology. ,vol. 109, pp. 432- ,(2014) , 10.1007/S00395-014-0432-Y

Mikiyasu Shirai, Daryl O. Schwenke, Hirotsugu Tsuchimochi, Keiji Umetani, Naoto Yagi, James T. Pearson, Synchrotron radiation imaging for advancing our understanding of cardiovascular function Circulation Research. ,vol. 112, pp. 209- 221 ,(2013) , 10.1161/CIRCRESAHA.111.300096