Protective interleukin-28B genotype affects hepatitis C virus clearance, but does not contribute to HIV-1 control in a cohort of African–American elite controllers/suppressors
作者： Maria Salgado , Gregory D Kirk , Andrea Cox , Alleluiah Rutebemberwa , Yvonne Higgins
DOI: 10.1097/QAD.0B013E328341B86A
关键词: Virology 、 Single-nucleotide polymorphism 、 Biology 、 Viral load 、 Hepatitis C virus 、 SNP 、 Immunology 、 Interleukin 、 Interleukin 28B 、 Genotype 、 Hepacivirus
摘要: We tested the hypothesis that a single nucleotide polymorphism (SNP) located near interleukin-28B gene is associated with control of hepatitis C virus and HIV-1 replication in elite controllers/suppressors. show here protective genotype not overrepresented controllers/suppressors compared HIV-1-seronegative patients HIV-1-infected viral loads more than 10 000 copies/ml. Thus, it appears this SNP infection.
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