Methods for identifying agonists and antagonists of human T-type calcium channels
作者： David L. Baillie , Terry P. Snutch
DOI:
关键词: Cell culture 、 T-type calcium channel 、 Complete sequence 、 Biology 、 Voltage-dependent calcium channel 、 Calcium channel 、 Biochemistry
摘要: Sequences and partial sequences for three types of mammalian (human rat) identified) T-type calcium channel subunits which we have labeled as the α 1G , 1H 1I are provided. Knowledge sequence these permits localization recovery complete from human cells, development cell lines express novel channels invention. These cells may be used identifying compounds capable acting agonists or antagonists to channels.
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