Studies on the inhibition of proteolytic enzymes by serum. II. Demonstration that separate proteolytic inhibitors exist in serum; their distinctive properties and the specificity of their action.

作者: N. Raphael Shulman

DOI: 10.1084/JEM.95.6.593

关键词: TrypsinProteolysisChymotrypsinProteolytic enzymesMolecular biologyKunitz STI protease inhibitorTrypsin inhibitorPlasminChemistryBiochemistryEnzyme

摘要: Increases in serum proteolytic inhibition with disease were found to be specific either for plasmin or trypsin and chymotrypsin. In normal serum, the inhibitor could differentiated from chymotrypsin by various physical chemical means. There was no apparent difference between serum. No qualitative differences inhibitors of sera showing elevated inhibition.

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