The lack of age as a significant prognostic factor in nonmetastatic breast cancer
作者： A. Ezzat , M.A. Raja , F. Zwaan , M. Brigden , A. Rostom
DOI: 10.1016/S0748-7983(98)80120-0
关键词: Mammary gland 、 Gynecology 、 Survival analysis 、 Prognostic factor 、 Internal medicine 、 Hormone therapy 、 Breast cancer 、 Younger age 、 Relapse free survival 、 Radiation therapy 、 Medicine
摘要: Aims To determine the prognostic significance of age at diagnosis in women with non-metastatic breast cancer. Methods A retrospective review all newly diagnosed cancer between 1975 and 1991 was carried out a tertiary Oncology Referral Centre. Patients were divided into three groups: 50 years. Demographic management/outcome details collected from patients UICC stages I–III. The effect on overall relapse free survival analysed by standard statistical methods. Results Of 1289 new cases registered during study period, 710 (55%) latter group 250 (35%) less than 40 years, 237 (33%) years 223 (32%) older Women younger had higher proportion breast-conserving surgery, adjuvant chemo- radiation therapy, while hormone therapy usage women. There no difference ( P =0.64) relapse-free =0.53) groups. Conclusion In this study, not factor predicting or
elsevier.com
sci-hub.se 参考文章(13)
David R. Cox, Regression Models and Life-Tables Springer Series in Statistics. ,vol. 34, pp. 527- 541 ,(1992) , 10.1007/978-1-4612-4380-9_37
A. de la Rochefordière, F. Campana, J. Fenton, J.R. Vilcoq, A. Fourquet, B. Asselain, S.M. Scholl, P. Pouillart, J.-C. Durand, H. Magdelenat, Age as prognostic factor in premenopausal breast carcinoma. The Lancet. ,vol. 341, pp. 1039- 1043 ,(1993) , 10.1016/0140-6736(93)92407-K
J M Kurtz, J Jacquemier, R Amalric, H Brandone, Y Ayme, D Hans, C Bressac, J M Spitalier, Why are local recurrences after breast-conserving therapy more frequent in younger patients? Journal of Clinical Oncology. ,vol. 8, pp. 591- 598 ,(1990) , 10.1200/JCO.1990.8.4.591
A J Nixon, D Neuberg, D F Hayes, R Gelman, J L Connolly, S Schnitt, A Abner, A Recht, F Vicini, J R Harris, Relationship of patient age to pathologic features of the tumor and prognosis for patients with stage I or II breast cancer. Journal of Clinical Oncology. ,vol. 12, pp. 888- 894 ,(1994) , 10.1200/JCO.1994.12.5.888
E. L. Kaplan, Paul Meier, Nonparametric Estimation from Incomplete Observations Springer Series in Statistics. ,vol. 53, pp. 319- 337 ,(1992) , 10.1007/978-1-4612-4380-9_25
Abram Recht, James L. Connolly, Stuart J. Schnitt, Barbara Silver, Mary Ann Rose, Susan Love, Jay R. Harris, The effect of young age on tumor recurrence in the treated breast after conservative surgery and radiotherapy. International Journal of Radiation Oncology Biology Physics. ,vol. 14, pp. 3- 10 ,(1988) , 10.1016/0360-3016(88)90043-0
Barbara L. Fowble, Delray J. Schultz, Beth Overmoyer, Lawrence J. Solin, Kevin Fox, Lori Jardines, Susan Orel, John H. Glick, The influence of young age on outcome in early stage breast cancer. International Journal of Radiation Oncology Biology Physics. ,vol. 30, pp. 23- 33 ,(1994) , 10.1016/0360-3016(94)90515-0
Joaquin Sariego, Steven Zrada, Michael Byrd, Teruo Matsumoto, Breast cancer in young patients American Journal of Surgery. ,vol. 170, pp. 243- 245 ,(1995) , 10.1016/S0002-9610(05)80007-8
Joseph P. Crowe, Age Does Not Predict Breast Cancer Outcome Archives of Surgery. ,vol. 129, pp. 483- 488 ,(1994) , 10.1001/ARCHSURG.1994.01420290029004
M.A. Richards, P. Smith, I.S. Fentiman, W.M. Gregory, R.R. Millis, R.D. Rubens, Age as prognostic factor in premenopausal breast cancer. The Lancet. ,vol. 341, pp. 1484- 1485 ,(1993) , 10.1016/0140-6736(93)90932-7