CONGENITAL RUBELLA SYNDROME IN THE UNITED STATES, 1970–1985 ON THE VERGE OF ELIMINATION

摘要: The National Congenital Rubella Syndrome Registry, a passive surveillance system, and the Birth Defects Monitoring Program, newborn hospital discharge data set, are used to monitor incidence of congenital rubella syndrome in United States. Reports registry contain clinical laboratory which allow cases be classified into six categories according likelihood having syndrome. monitoring program records diagnoses, without detailed information, nonrandom sample about one fourth births States annually. To evaluate two systems estimate actual syndrome, authors collected summaries on all as reported by from 1970-1985 them criteria. Of 392 during 1970-1985, 24% (n = 93) could confirmed or compatible compared with 79% 415) 526 (rate ratio 3.3; 95% confidence interval (CI) 2.9-3.8). Diagnosis was made neonatal period for 68% (263 389) whom such were available. When Lincoln-Peterson capture-recapture method estimating population size independent used, an estimated 1,064 (95% CI 668-1,460) diagnosed occurred 1970-1979, average 106 per year. During 1980-1985, 122 8-236) occurred, 20 A downward secular trend beginning 1980 observed. detected 22% cases, 8%, combined total 28%. results indicate that may verge elimination