Exposure to early androgen attenuates androgen induced pup-killing in male and female mice

作者: Ronald Gandelman , Frederick Vom Saal

DOI: 10.1016/S0091-6773(77)90825-2

关键词: Exposure periodEndocrinologyInternal medicineTestosterone propionateAndrogenBiologyGeneral Earth and Planetary SciencesGeneral Environmental Science

摘要: Adult virgin female mice administered testosterone propionate (TP) on Day 0, 4, or 8 of life require a longer TP exposure period in adulthood to induce pup-killing than do animals given 12 21 oil 0. Significantly fewer males gonadectomized 60 killed pups response treatment as compared Days 0 and 4. that did kill young required These data suggest early androgen reduces the effectiveness later inducing pup-killing.

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