The mammalian central pattern generator for locomotion

摘要: At the beginning of 20th century, Thomas Graham Brown conducted experiments that after a long hiatus changed views on neural control locomotion. His seminal work supported by subsequent evidence generated largely from 1960s onwards showed across species walking, flying, and swimming are controlled neuronal network has been referred to as central pattern generator (CPG) for In mammals, this caudally localized spinal cord was found generate basic command signals sent muscles limbs locomotor rhythm generation. This article constitutes comprehensive review summarizing key findings organization properties network.