Genetic Protein Polymorphisms in Human Saliva: An Interpretive Review
作者： Edwin A. Azen
DOI: 10.1007/BF00484386
关键词: Salivary Proteins 、 Phenotype 、 Biology 、 Genetics 、 Allele 、 Saliva 、 Human genetics
摘要: The purpose of this review is to summarize recent progress in the field genetic protein polymorphisms found human saliva since 1972. Prior 1972 most investigations were related amylase. genetics salivary amylase will not be considered here, it has recently been thoroughly reviewed elsewhere (Merritt and Karn, 1977). In review, special attention devoted complex interrelationships proline-rich (Pr), double-band (Db), acidic (Pa), peroxidase (SAPX) systems. biochemically Pr, Db, Pa systems show distinctive patterns, there are associations between phenotypes indicating linkage relationships. There also evidence for probable interaction products SAPX loci. Electrophoretic properties these proteins can defined several gel systems, permitting an accurate definition phenotypes. usefulness limitations different interpretation electrophoretic patterns illustrated. Allelic frequencies discussed given Table I. To aid comprehension, logical rather than historical sequence.
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