Smell and Taste Disorders in COVID-19 Patients: Objective Testing and Magnetic Resonance Imaging in Five Cases.
作者： Carmen Maria Schönegger , Sarah Gietl , Bernhard Heinzle , Kurt Freudenschuss , Gernot Walder
DOI: 10.1007/S42399-020-00606-4
关键词: Disease 、 Dysgeusia 、 Taste 、 Magnetic resonance imaging 、 Dermatology 、 Dysosmia 、 Coronavirus disease 2019 (COVID-19) 、 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 、 Taste disorder 、 Medicine
摘要: Smell and taste disorders are acknowledged as characteristic symptoms for SARS-CoV-2 infection by now. These have been linked to a neuroinvasive course of disease. In this study, we investigated five consecutive COVID-19 patients with prolonged dysosmia dysgeusia. Those objectifiable alteration in or smell were subjected MRI contrast agent investigate possible involvement the central nervous system. We found dysgeusia be mostly objectifiable, but no evidence neuroinvasiveness could detected late stage Alterations objectified most patients. Nevertheless, potential identified MRI, at least encourage medical professionals conduct specialized examinations MRIs acute disease, which guarantees an optimum patient care.
springer.com
sci-hub.st 参考文章(20)
F J Carod-Artal, Complicaciones neurológicas por coronavirus y COVID-19./ Complicaciones neurológicas por coronavirus y COVID-19./ Neurological complications of coronavirus and COVID-19. Revue Neurologique. ,vol. 70, pp. 311- 322 ,(2020)
Letterio S. Politi, Ettore Salsano, Marco Grimaldi, Magnetic Resonance Imaging Alteration of the Brain in a Patient With Coronavirus Disease 2019 (COVID-19) and Anosmia. JAMA Neurology. ,vol. 77, pp. 1028- 1029 ,(2020) , 10.1001/JAMANEUROL.2020.2125
Valeria Dell’Era, Filippo Farri, Giacomo Garzaro, Miriam Gatto, Paolo Aluffi Valletti, Massimiliano Garzaro, Smell and taste disorders during COVID-19 outbreak: Cross-sectional study on 355 patients. Head and Neck-journal for The Sciences and Specialties of The Head and Neck. ,vol. 42, pp. 1591- 1596 ,(2020) , 10.1002/HED.26288
Benoit Tudrej, Paul Sebo, Julie Lourdaux, Clara Cuzin, Martin Floquet, Dagmar M. Haller, Hubert Maisonneuve, Self-Reported Loss of Smell and Taste in SARS-CoV-2 Patients: Primary Care Data to Guide Future Early Detection Strategies. Journal of General Internal Medicine. ,vol. 35, pp. 2502- 2504 ,(2020) , 10.1007/S11606-020-05933-9
Antje Haehner, Julia Draf, Sarah Dräger, Katja de With, Thomas Hummel, Predictive Value of Sudden Olfactory Loss in the Diagnosis of COVID-19. Operations Research Letters. ,vol. 82, pp. 175- 180 ,(2020) , 10.1159/000509143
B. N. Landis, A. Welge-Luessen, A. Brämerson, M. Bende, C. A. Mueller, S. Nordin, T. Hummel, “Taste Strips” – A rapid, lateralized, gustatory bedside identification test based on impregnated filter papers Journal of Neurology. ,vol. 256, pp. 242- 248 ,(2009) , 10.1007/S00415-009-0088-Y
T. Hummel, G. Kobal, H. Gudziol, A. Mackay-Sim, Normative data for the "Sniffin' Sticks" including tests of odor identification, odor discrimination, and olfactory thresholds: an upgrade based on a group of more than 3,000 subjects. European Archives of Oto-rhino-laryngology. ,vol. 264, pp. 237- 243 ,(2007) , 10.1007/S00405-006-0173-0
Marc Desforges, Alain Le Coupanec, Philippe Dubeau, Andréanne Bourgouin, Louise Lajoie, Mathieu Dubé, Pierre J. Talbot, Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? Viruses. ,vol. 12, pp. 14- ,(2019) , 10.3390/V12010014
Abdul Mannan Baig, Areeba Khaleeq, Usman Ali, Hira Syeda, Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host–Virus Interaction, and Proposed Neurotropic Mechanisms ACS Chemical Neuroscience. ,vol. 11, pp. 995- 998 ,(2020) , 10.1021/ACSCHEMNEURO.0C00122
Neo Poyiadji, Gassan Shahin, Daniel Noujaim, Michael Stone, Suresh Patel, Brent Griffith, COVID-19-associated Acute Hemorrhagic Necrotizing Encephalopathy: Imaging Features. Radiology. ,vol. 296, pp. 201187- ,(2020) , 10.1148/RADIOL.2020201187