High rate of aminoglycoside resistance among staphylococci causing prosthetic joint infection.

作者: Paloma Anguita-Alonso , Arlen D Hanssen , Douglas R Osmon , Andrej Trampuz , James M Steckelberg

DOI: 10.1097/01.BLO.0000182394.39601.9D

关键词: Staphylococcus aureusAminoglycoside resistanceGentamicinMicrobiologyHigh rateMedicineTobramycinProsthetic joint infection

摘要: Gentamicin and tobramycin are two aminoglycosides commonly impregnated into polymethylmethacrylate for treatment prevention of prosthetic joint infection. Susceptibilities staphylococci to not reported routinely in the United States. The gentamicin minimum inhibitory value 93 from patients with PJI were determined. Forty-one 66% isolates resistant tobramycin, respectively. Methicillin-resistant Staphylococcus aureus more likely be or than their methicillin susceptible counterparts. findings suggest that consideration should given further study agents other incorporation

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