Is there a requirement for adjuvant therapy for choroid plexus carcinoma that has been completely resected

摘要: Choroid plexus carcinomas (CPC) are rare central nervous system malignancies. While attempted surgical resection is imperative, the benefit of adjuvant therapy, particularly in setting a gross total (GTR), unclear. We reviewed all pediatric cases CPC reported literature between 1985 and 2000. Seventy-five were identified. Mean age at time diagnosis was 26 months. Thirty-seven patients had GTR 38 subtotal (STR). Thirty-eight (51%) alive 37 (49%) deceased publication. For with GTR, survival 84% compared to an 18% for STR. forms therapy statistically equivalent. Our retrospective review confirms importance CPC, alone being single most important predictor survival. The prognosis poor any patient STR, exception those whom allowed eventual GTR. small number receiving no further precluded statistical comparison versus form therapy. However, four these alive, raising possibility that may not be required.