Toxicological Studies in Insects

摘要: The body surface of insects consists a hard skin known as the cuticle. At first glance it appears that this barrier should be very effective against entry insecticides, but there are two main reasons why is not: (1) insect exposes far greater area relative to its volume than mammal, and (2) cuticle hydrophobic (i.e., lipophilic) so can resist desiccation drowning. Most modern insecticides apolar therefore easily penetrate Mammalian skin, by contrast, relatively resistant insecticides. As result, common acute oral toxicity an insecticide much higher in mammals contact toxicity, where toxicities almost equal insects. Though cuticular penetration usually major pathway, some instances do enter way mouth, respiratory system, other vulnerable places such antennae, eyes, tarsi.